C6143
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C6143
Sigma
Chlorhexidine diacetate salt hydrate
| Synonym: | 1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide) |
| CAS Number: | 56-95-1 |
| Linear Formula: | C22H30Cl2N10 · 2C2H4O2 |
| Molecular Weight: | 625.55 |
| EC Number: | 200-302-4 |
| MDL number: | MFCD00012532 |
| PubChem Substance ID: | 24892838 |
Description
| Biochem/physiol Actions | Cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs. |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
| WGK Germany | 3 |
| RTECS | DU1930000 |
References
| reference | Barrett-Bee, K., et al., The membrane destabilising action of the antibacterial agent chlorhexidine. FEMS Microbiol. Lett. 119, 249-253, (1994) |
